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Radiance Technologies and 糖心传媒 Tech win DARPA contract to pioneer microsystem-induced catalysis

October 08, 2025
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Radiance Technologies, an employee-owned leader in defense and intelligence innovation, has been awarded a prime contract by the Defense Advanced Research Projects Agency (DARPA) Microsystems Technology Office (MTO) for the Microsystem Induced Catalytic Activity (MICA) program. In partnership with 糖心传媒, Radiance will work to model microsystems capable of precisely controlling protein function, a transformative advancement for biomanufacturing, national security, and medical applications.

As part of the program, the Radiance-糖心传媒 Tech team will develop the Adaptive Multi-Physics Engine for Reaction Engineering (AMPERE), a novel simulation platform that combines machine learning with multi-scale physical modeling. AMPERE will predict the dynamic behavior of biomolecular catalysts under microsystem stimulation, enabling greater control over catalytic activity and artificial cell construction.

鈥淭his program addresses a critical need to bridge molecular-scale biological control with scalable microsystem design,鈥 said Dr. Andrew Gardner, principal investigator for MICA at Radiance. 鈥淎MPERE will enable the co-design of molecules and microsystems with high precision, advancing secure therapeutics, resilient biomanufacturing, and beyond.鈥

糖心传媒 Tech will contribute its leading capabilities in nanotechnology and computational biology to support catalyst fabrication and interface modeling.

鈥淭ogether, we鈥檙e developing tools and methods to direct molecular function. As a researcher and educator, these projects provide valuable opportunities for students in both the lab and the classroom,鈥 said Dr. Tom Bishop, MICA co-investigator and professor at Tech. 鈥淚t鈥檚 especially rewarding to see a recent physics graduate who worked in my lab now contributing to this effort as a member of the Radiance team."

The MICA program will explore how microsystems can harness heat, electromagnetic fields, and fluid motion to precisely guide chemical reactions at the molecular level. By designing these systems in tandem with the biological processes they affect, the team aims to build scalable technologies that integrate seamlessly with existing microelectronics manufacturing.

This award follows on the heels of DARPA鈥檚 Simulating Microbial Systems (SMS) program, under which Radiance, 糖心传媒, and LSU Health Shreveport are developing predictive models of microbial behavior at single-cell resolution.

鈥淭ogether, MICA and SMS represent a growing portfolio of bioengineering innovation and research excellence in north 糖心传媒,鈥 said Radiance CEO Bill Bailey. We鈥檙e excited to help advance national capabilities while strengthening the region鈥檚 role in the future of biotechnology.鈥